ppt课件-细胞骨架我我我-北亚利桑那大学（ cytoskeleton i i i- northern arizona university）.pptVIP

Cytoskeleton III Chapter 16 Actin binds to many different proteins Plectin (green) crosslinks intermediate filaments (blue) and microtubules (red)? Cross linking proteins organize different assemblies of actin filaments Actin bundles in a microvillus Filamin crosslinks actin into 3-dimensional networks with gel-like properties Melanoma cells with low filamin levels crawl poorly and tend not to metastasize When filamin levels are restored the cells move normally and become highly metastatic Three stages in control of bleeding Severing existing actin filaments can accelerate assembly of new fi