八珍汤加味治疗围绝经期综合征65例疗效观察.docVIP

八珍汤加味治疗围绝经期综合征65例疗效观察 nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 作者：张书琴 谷守星 王金荣 【摘要】nbsp; 　　目的 观察八珍汤加味治疗围绝经期综合征的临床疗效。方法 将125例围绝经期综合征患者随机分为2组。治疗组65例予八珍汤加味，每日1剂，水煎分2次服。对照组60例予尼尔雌醇，每次2 mg，每2周服1次。2组均1个月为1个疗程，连续治疗3个疗程。观察2组临床疗效、症状治疗前后的改善情况及不良反应情况。结果 2组治疗后主要症状均有不同程度改善，与本组治疗前比较差异均有统计学意义（P＜0.01），2组治疗后比较差异均无统计学意义（P＞0.05）；2组总有效率及愈显率比较差异均无统计学意义（Pgt;0.05）；2组不良反应发生率比较差异有统计学意义（Plt;0.01）。结论 应用八珍汤加味以益气养血法治疗围绝经期综合征和雌激代素替疗法有相等的临床疗效，且不良反应少。 【关键词】nbsp; 更年期综合征 八珍汤 雌激素类 　　The observation on therapeutic effect of Bazhen decoction on 65 Cases with premenopausal Syndrome nbsp;nbsp;nbsp; 　　【Abstract】nbsp; Objectivenbsp; To observe the therapeutic effect of Bazhen decoction on the premenopausal syndrome. Methodsnbsp; 125 patients were randomly divided into 2 groups. The 65 patients in treatment group were treated by Bazhen decoction one dose a day. The control group was treated by Nitestriol 2mg each time, once every two weeks. Both of their treatment courses were one month and were continuously observed for three courses after which the effects were evaluated. Resultsnbsp; The curative and effective rates in the treatment group were 83.1% and 92.3% ,which were superior to 76.7% and 90.0% in the control group, respectively. There were no statistical differences between two groups. Side effect in the treated group was obviously less than that of the control group (Plt;0.05). Conclusionnbsp; Bazhen decoction and estrogen replacement therapy have the same therapeutic effects on premenopausal symptoms, while the side effects in treatment group are much less. nbsp;nbsp;nbsp; 　　【Key words】nbsp; Premenopausal syndrome; Bazhen decoction; Estrogens 　　围绝经期综合征是女性在绝经前后卵巢分泌的雌激素水平波动或下降所致的以自主神经系统功能紊乱为主，伴有神经心理症状的一组综合征以及低雌激素水平的相关症状。2005-07—2007-07，我们采用八珍汤加味治疗围绝经期综合征65例，并与尼尔雌醇治疗60例对照观察，现报告如下。 　　1nbsp; 资料与方法 　　1.1nbsp; 一般资料nbsp; 全部125例均为本院中医科、妇科门诊及住院患者，年龄42～56岁，平均(49±7)岁，随机分为2组。治疗组65例，年龄42～55岁，平均（50±5）岁；病程2个月～3年，平均1.5年；伴随症状：潮热60例，月经紊乱65例，心悸失眠、烦躁易怒45例，眩晕耳鸣42例，烘热汗出58例，面目下