老年原发性高血压与骨密度的关系.docVIP

老年原发性高血压与骨密度的关系 　　[摘要] 目的 探讨60岁以上老年人原发性高血压与骨密度的关系。 方法 选取60岁以上人群162例，其中原发性高血压患者82例，对照组80例，分别测量身高、体重、计算体重指数，血压。用双能X线骨密度仪检测左前臂中段、左股骨颈、腰椎（L1～4）及全身骨密度。 结果 高血压组的上肢、下肢、腰椎及全身骨密度均低于对照组（P0.05）。校正年龄、身高、体重、BMI后收缩压与上肢、下肢、腰椎及全身骨密度呈负相关（P0.05），舒张压与骨密度无关。检测人群中骨量异常组收缩压及舒张压均高于骨量正常组（P0.05）。 结论 老年人群中高血压与骨密度有关，老年高血压患者各部位骨密度均减低，收缩压与骨密度呈负相关，控制收缩压可能对于老年人预防骨质疏松有一定作用，同时对老年高血压人群积极防控骨质疏松可能有助于血压的控制。 　　[关键词] 老年；原发性高血压；骨密度 　　[中图分类号] R544.1 [文献标识码] A [文章编号] 2095-0616（2015）14-20-03 　　The relationship between primary hypertension and bone mineral density in old person 　　LU Donghui LIN Yuan ZHANG Fan 　　Department of Endocrinology， Peking University Shenzhen Hospital， Shenzhen 518036， China 　　[Abstract] Objective To observe the relationship between primary hypertension and bone mineral density in adults over 60-year old. Methods 82 hypertension patients and 80 controllers over 60-year old were recruited.The height、weight、body mass index and blood pressure were measured .It was also detected the middle of left forearm，left femoral neck， the 1-4 lumbar spine and the whole body bone mineral density（BMD） by dual energy X-ray absorptiometry. Results The BMD of upper limbs、lower limbs、lumbar spine and whole body in hypertension group were lower than control group（P0.05）. After adjustment of age、height、weight and BMI， systolic blood pressure has negative correlation with the BMD of upper limbs、lower limbs、lumbar spine and whole body（P0.05）. But there was no correlation between diastolic blood pressure and BMD. In all subjects，osteopenia and osteoporosis group have higher systolic blood pressure and diastolic blood pressure compared with normal bone mass group. Conclusion Hypertension bave correlation with BMD in old persons. Old hypertension patients BMD were lower than controllers. Systolic blood pressure was negative correlated with BMD. So well controlling of systolic blood pressure maybe has positive effect on prevention osteoporosis in old hypertensive patients. Prevetion and treatment osteopo