digestionandthe digestive system- universityof baghdad（digestionandthe消化系统——巴格达大学）（65页）.docVIP

Biochemistry of Digestion, Absorption and Detoxification 27/9-9/10/2011 Lecture 1: Introduction to the Biochemistry of Digestion, absorption and detoxification. Lecture 2: Digestion and Digestive secretion from mouth and stomach Lecture 3: Digestive secretion from pancreas and liver Lecture 4: Detoxification in the liver Lecture 5: Secretion and absorption in the small intestine Lecture 6: Secretion and absorption in the large intestine Aim and objective of the above six lectures is to understand: The biochemistry and mechanism of digestion of food The absorption of basic nutrients The detoxification mechanism References: Biochemistry by Lubert Stryer (textbook) Textbook of Biochemistry with Clinical Correlations by T.M.Devlin (additional reading) Lippincotts Illustrated Reviews in Biochemistry by P.C.Champe, R.A.Harvey and D.R.Ferrier (additional reading) Harpers Biochemistry by R.K.Murray, D.K.Granner, P.A. Mayes and V.W.Rodwell. (additional reading) LECTURE 1 Tuesday 27/9/2011 Introduction to the Biochemistry of Digestion, Absorption and Detoxification Introduction Digestion is the chemical breakdown of large food molecules into smaller molecules that can be used by cells. The breakdown occurs when certain specific enzymes are mixed with the food. Enzymes involved in Digestion polysaccharides ? maltose ? glucose proteins ? peptides ? amino acids fats fatty acids and glycerol LECTURE 1 Tuesday 27/9/2011 Review of Food Chemistry The diet of any animal contains hundreds if not thousands of different molecules, but the bulk of the ingested nutrients are in the form of huge macromolecules that cannot be absorbed into blood without first being reduced to much simpler and smaller forms. The most important enzymatic reaction in digestion of foodstuffs is hydrolysis - the breaking of a chemical bond by the addition of a water molecule. Proteins Proteins are polymers of amino acids