性别和体重动脉硬化[精选].docVIP

性别与体重对心踝指数测量值的影响 李方洁 袁晓春 郭小玉 于骋 中国中医科学院望京医院 100102 『摘要』目的 探讨性别与体重对心踝指数（CAVI）的影响。方法 以445例接受CAVI检测的正常人为观察对象，按年龄分为＜45岁和≥45岁两组。使用VaSeraTM VS-1000动脉硬化检测仪，对两组观察对象进行CAVI检测，采用多元线性逐步回归的统计学方法，以CAVI值为因变量，以年龄、性别、收缩压（SBP）、舒张压（DBP）、脉压（PP）、体重指数（BMI）为自变量进行数据处理，观察不同年龄组性别和体重指数（BMI）对CAVI测量值的影响。结果：＜45岁组中性别、年龄、BMI被引入回归方程，标准化回归系数分别为-0.333(性别)、0.275(年龄)、-0.232(BMI)，女性CAVI值小于男性；≥45岁组中，年龄、SBP、BMI被引入回归方程，标准化回归系数分别为0.439(年龄)、0.295(SBP)、-0.274(BMI)；性别未引入方程。在两组中，BMI均与CAVI值呈负相关。结论 本组资料显示，中青年女性CAVI检测值低于同龄男性，而中老年女性与同龄男性无显著差异。提示除年龄和血压这些较为公认的因素外，性别也可能对CAVI检测值有一定的影响。本研究结果显示BMI和CAVI呈负相关，而关于BMI对CAVI影响的观察较少，有待进一步关注，机理有待探讨。 『关键词』 CAVI；性别；体重指数 Abstract Objective To study the clinical correlation factors which can effect people’s Cardio Ankle Vascular Index (CAVI) and the difference with the pulse wave velocity (PWV)for right applications of the inspection. Methods The observed objects are 1014 volunteers. We collect the subjects’ case history and use the detectors of VaSeraTM VS-1000 angiosclerosis to measure CAVI. In addition 321 cases of all subjects are also measured the PWV. Then we deal with the data using multiple linear regression statistical method to observe the effect of age, sex, disease and blood pressure on the CAVI measure value. Result Analysis of the normal group shows that age, sex, and systolic blood pressure are all the impact factors of CAVI, but the impact of diastolic blood pressure is no statistically significant. CAVI have positively correlated with age, systolic blood pressure. Besides the CAVI value of female is less than male. And age is the significant independent impact factor. We study the impact of disease on CAVI. The results show that the high blood pressure group and the diabetes group are higher than the normal group, high blood pressure group is higher than the Hyperlipidemia group, but there is no difference between the Hyperlipidemia group and the normal/diabetes group. In addition, the study shows that systolic blood pressure is an important impact factors of