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ppt课件-titleof presentation-subtitleorsupportingstatement-（titleof presentation-subtitleorsupportingstatement -）.ppt

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* 12 Month LM Subgroup MACCE Rates CABG TAXUS All LMN=705 LM+1VDN=138 LM isolatedN=91 LM+2VDN=218 LM+3VD N=258 Patients (%) 12 Month Subgroup MACCE Rates All LMN=705 LM+1VDN=138 LM isolatedN=91 LM+2VDN=218 LM+3VD N=258 Patients (%) 3VD (All) N=1095 CABG TAXUS Outcome according to Diabetic Status Diabetes (Medical Treatment) N=452 Non-Diabetic N=1348 TAXUS CABG Death/CVA/MI MACCE Death/CVA/MI MACCE P=0.96 P=0.0025 P=0.08 P=0.97 Conclusions: In the randomized SYNTAX cohort, there were comparable overall safety outcomes (Death, CVA, MI,) in CABG and PCI patients at 12 months (7.7 vs. 7.6 %). There was a significantly higher rate of revascularization in the PCI group (13.7 vs. 5.9 %), and a significantly higher rate of CVA in the CABG group (2.2 vs. 0.6 %). Overall MACCE in the PCI group was higher (17.8 vs.12.1 %) due to an excess of redo revascularization compared with CABG. Per protocol rates of symptomatic graft occlusion and stent thrombosis were similar. The SYNTAX score will help stratify patients for the appropriate revascularization option. * * * * * * in reg * * Katrin trying to get more pictures * * * * * * * Exhibit 6 * Exhibit 6 * Exhibits 10, 12 * Exhibits 18, 19 * Exhibit 33 * Exhibit 36 * Exhibit 37 * * Exhibit 2 * Exhibit 38 * * Exhibit 1 The Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery:The SYNTAX StudyPrimary Endpoint Results at One Year in the Randomized Cohort Patrick W. Serruys MD PhD Friedrich W. Mohr MD PhD On behalf of the SYNTAX investigators Conflicts of Interest: None During the present decade, major developments in CABG (e.g. off-pump technique, less invasive approach, increased arterial revascularization and optimal perioperative care). In PCI (e.g. improved technique, stent design, guide wires, anti-platelet therapy, and drug-eluting stents) have made it important to reassess the respective values of the two revascularization techniques in an all-comers population as seen by the surgeon a