2014中国心衰指南概览.ppt

* 自上世纪九十年代初，国际著名的心脏病学家哈佛大学医学院Braunwald教授提出了心血管事件链的概念，强调了从高血压、高血脂、高血糖等危险因素到动脉粥样硬化、冠心病、心肌梗死直至左室重构，心力衰竭这一连续的心血管事件的内在联系及发展趋势。 这一理论先后被美国心脏病学会（ACC）/美国心脏学会（AHA）、欧洲心脏协会ESC以及中国慢性性心衰指南所引用，把心力衰竭划分A、B、C、D四个阶段，因此心血管事件链的概念为慢性心衰从“防”到“治”提供了的新理念。 * In theory, there are four ways of reducing the heart sinus rate: By prolonging the action potential repolarization time By reducing maximal diastolic potential (more electronegative potential) By shifting the threshold potential to a more positive level By slowing the rate of diastolic depolarization This study shows that Procoralan only acts by reducing the slope of diastolic depolarization without significant changes in maximal diastolic potential In theory, there are four ways of reducing the heart sinus rate: By prolonging the action potential repolarization time By reducing maximal diastolic potential (more electronegative potential) By shifting the threshold potential to a more positive level By slowing the rate of diastolic depolarization This study shows that Procoralan only acts by reducing the slope of diastolic depolarization without significant changes in maximal diastolic potential In theory, there are four ways of reducing the heart sinus rate: By prolonging the action potential repolarization time By reducing maximal diastolic potential (more electronegative potential) By shifting the threshold potential to a more positive level By slowing the rate of diastolic depolarization This study shows that Procoralan only acts by reducing the slope of diastolic depolarization without significant changes in maximal diastolic potential In theory, there are four ways of reducing the heart sinus rate: By prolonging the action potential repolarization time By reducing maximal diastolic potential (more electronegative potential) By shifting the threshold potential to a more positive level By slowing the rate of diastolic depolarization This study shows that Procoralan only acts by reducing the slope of diastolic depolarization w