scifinder如何使用.pptVIP

导 航 Part I SciFinder背景介绍 Part II 检索技巧介绍 文献检索 物质检索 反应检索 Part III SciFinder Web 新功能 原文与SciFinder的摘要 The invention relates to protracted peptide derivatives such as Glucagon-Like Peptide-1 (GLP-1), exendin-4, and analogues thereof, as well as therapeutic uses thereof.The peptide derivative of the invention comprises a peptide wherein at least one amino acid residue is derivatized with A-B-C-, or A-B-C-D-. These compounds are useful in the treatment or prevention of diabetes type 2 and related diseases. The compounds are potent, have a low ratio of binding affinity to the GLP-