silencingofbidirectionalpromotersbydnamethylationin.pptVIP

Silencing of Bidirectional Promoters by DNA Methylation in Tumorigenesis by Jingmin Shu, Jaroslav Jelinek, Hao Chang, Lanlan Shen, Taichun Qin, Woonbok Chung, Yasuhiro Oki, and Jean-Pierre J. Issa Cancer Res Volume 66(10):5077-5084 May 15, 2006 ?2006 by American Association for Cancer Research Schematic illustration of three bidirectional promoters: (A) WNT9A/CD558500 promoter, (B) CTDSPL/BC040563 promoter, (C) KCNK15/BF195580 promoter. Jingmin Shu et al. Cancer Res 2006;66:5077-5084 ?2006 by American Association for Cancer Research Bisulfite sequencing in normal control and cell lines. Jing