Exploiting Protein Structure in the Postgenome Era后基因组时代的蛋白质结构.pptVIP

How the body has information telling it what to make and what to do How everything is made up of atoms How the body uses shape as its code How we use computer graphics to look at atoms and make drugs. Mrs Ben Ze’ev for suggesting this partnership The Royal Society for providing funds Dr Suhail Islam (Imperial College) for the movies My daughter for advice on what I should say and how I should make the slides * * ....blue eyes....blond hair... Instructions Genes DNA What is made Proteins ....blue eyes....blond hair...lungs… Smoking messes up the instructions and causes lung cancer Everything is made up of atoms Atoms are round There are different types of atoms Oxygen Hydrogen Iron If a tennis ball were magnified to the size of the earth An atom would be magnified to the size of a tennis ball A microscope uses light But to see atoms we use X-rays Only the right key will fit into the lock Instruction – gene or DNA Blue eye colour - protein We make a key that fits into the lock but does not turn We jam the way the germ works We make a key that fits into the lock but does not turn We jam the way the germ works My team use computers to crack the code of biology ....blue eyes..