超临界萃取技术在制药行业中的应用.doc

目录 摘要 1 关键字 1 一、 超临界流体 2 二、超临界流体萃取原理 2 三、 超临界流体萃取技术在中药有效成分的应用 3 1、萜类和挥发油的提取 3 2、 黄酮类化合物的提取 3 四、 超临界流体技术在医药工业中的应用 3 五、超临界ＣＯ，萃取在药物分析中的应用 3 六、ＳＣＦ微粒化技术及在药物微粒化制备中的应用 4 七、超临界流体快速膨胀过程（ＲＥＳＳ） 4 八、超临界流体抗溶剂过程（ＳＡＳ） 5 十、结束语 5 参考文献 6 超临界萃取技术在制药中的应用摘要：简要介绍了超临界流体萃取的基本原理及其在制药中的应用对超临界流体技术在中药现代化与新药研究中的应用情况进行概述，展现了该技术在药物研究领域具有广阔发展前景和实际应用价值超临界流体快速膨胀过程（ＲＥＳＳ超临界流体抗溶剂过程（ＳＡＳ重点阐述了超临界流体萃取用于药用成分提取和分析，超临界流体微粒化及其在药物微粒化制备上的应用，分析了超临界流体技术在制药行业开发和应用中的问题，展望了超临界流体技术的应用前景。超临界流体技术作为中药现代化关键技术，在制药工程中具有独特的优势，理论基础研究和相关研究还需要加强。随着研究的深入和认识的加强，超临界流体技术作为一项可持续的绿色工艺，将具有广泛的应用前景。 超临界流体萃取中药 提取应用快速膨胀抗溶剂 Abstract: this article introduces the basic principle of supercritical fluid extraction and its application in the pharmaceutical industry, the supercritical fluid technology in the modernization of traditional Chinese medicine and the application of new drug research are summarized, show the technology in drug research field has the broad prospects for development and actual application value. The supercritical CO2 extraction is the most commonly used, the rapid expansion of supercritical fluid process (RESS) and supercritical fluid resistance to solvent process (SAS) in drug extraction and separation plays a vital role. Focus on the supercritical fluid extraction used for medicinal component extraction and analysis, supercritical fluid pelletizing and in drug pelletizing preparation of the application, analysis of the supercritical fluid technology in the pharmaceutical industry development and the problems in use, and looks forward to the application prospect of supercritical fluid technology. Supercritical fluid technology as key technology modernization of traditional Chinese medicine, in the pharmaceutical engineering has unique advantages, the theoretical basic research and related research also need to strengthen. With the deepening of research and understanding of the strengthen, supercritical fluid technology as a sustainable green technology, has a broad prospect of application. Key word: supe