24 h动态血糖监测在妊娠期糖尿病患者中对妊娠结局的影响.docVIP

24 h动态血糖监测在妊娠期糖尿病患者中对妊娠结局的影响 　　[摘要] 目的 探讨动态血糖监测系统（CGMS）对妊娠期糖尿病（GDM）患者妊娠结局的影响。 方法 选择2011年1月～2012年12月在深圳市龙岗区人民医院就诊的GDM患者60例，分为A组和B组，每组各30例。A组患者给予24 h动态血糖监测，B组行常规末梢血糖检查，未予动态血糖监测。统计并比较：①两组孕妇妊娠高血压综合征、早产、宫内感染、羊水过多、胎膜早破、剖宫产等围生期并发症发生率；②两组新生儿高胆红素血症、低血糖、围生儿死亡、新生儿窒息、巨大儿的发生率及新生儿体重及新生儿胎龄情况。 结果 ①B组妊娠高血压综合征[13.33%（4/30）]、早产[6.67%（2/30）]、宫内感染[6.67%（2/30）]、羊水过多[6.67%（2/30）]、胎膜早破[10.00%（3/30）]、剖宫产[53.33%（16/30）]发生率明显高于A组[6.67%（2/30）、3.33%（1/30）、0.00%（0/30）、0.00%（0/30）、3.33%（1/30）、40.00%（12/30）]，差异均有统计学意义（P 0.05）。②两组围生儿并发症比较，B组高胆红素血症[13.33%（4/30）]、低血糖[6.67%（2/30）]、新生儿体重[（3345±512）g]、新生儿窒息[6.67%（2/30）]、巨大儿[6.67%（2/30）]等项均明显高于A组[6.67%（2/30）、0.00%（0/30）、（3045±460）g、0.00%（0/30）、0.00%（0/30）]，差异均有统计学意义（P 0.05）。结论 CGMS能为需要治疗的GDM患者提供早期的动态血糖监测，为后续的治疗提供更准确的血糖依据，是有效降低母婴并发症和合并症的监测方法之一。 　　[关键词] 动态血糖监测；妊娠期糖尿病；妊娠结局 　　[中图分类号] R714.25[文献标识码] B[文章编号] 1673-7210（2014）06（a）-0143-04 　　 　　Effect of continuous glucose monitoring system to pregnancy outcome in gestational diabetes mellitus 　　WANG Juan1 CHEN Xuejing1 YANG Xiangju1 CHEN Liuhua1 GUO Zhongqiu1 WANG Xiumei2 CHEN Yuhua1 　　1.Department of Endocrinology and Metabolism, Longgang District Peoples Hospital of Shenzhen City, Guangdong Province, Shenzhen 518172, China; 2.Department of Gynaecology and Obstetrics, Henggang Peoples Hospital in Longgang District of Shenzhen City, Guangdong Province, Shenzhen 518172, China 　　[Abstract] Objective To investigate the influence of pregnancy outcome in GDM patients by continuous glucose monitoring system (CGMS). Methods 60 patients with GDM in Longgang District Peoples Hospital of Shenzhen City from January 2011 to December 2012 were selected and divided into group A and group B with 30 cases in each group. The group A was treated with continuous glucose monitoring for 24 h, group B was treated with normal peripheral blood sugar checking without continuous glucose monitoring. The indexes were observed and compared: ①the occurrence rate of perinatal complications of pregnancy induced hypertension, prem