内镜下套扎术联合药物治疗食管静脉曲张出血的效果.docVIP

内镜下套扎术联合药物治疗食管静脉曲张出血的效果 　　[摘要] 目的 探讨食管静脉曲张出血行内镜下套扎术联合药物治疗的效果。 方法 选择2011年10月～2013年10月在浙江省湖州市中心医院诊治的食管静脉曲张出血患者124例，按照随机数字表法分成两组，每组各62例，对照组予以内镜下套扎术联合常规止血抗炎药物治疗，研究组予以内镜下套扎术与泮托拉唑、生长抑素、普萘洛尔等联合药物治疗，分析不同分级的再出血、两组止血效果、并发症情况。 结果 不同Child-Pugh分级再出血率比较，Child-Pugh C级明显高于Child-Pugh A及B组，差异有统计学意义（P 0.05）。且研究组出血再发率为3.23%，复发率为6.45%，比对照组（19.35%、24.19%）降低，差异有统计学意义（P 0.05）。同时研究组伴发食管溃疡、门脉高压胃病发生率为3.23%、3.23%，比对照组（19.35%、20.97%）降低，差异有统计学意义（P 0.05）。 结论 针对食管静脉曲张出血患者，予内镜下套扎术与联合药物治疗，患者的止血效果良好，且并发症较少，具有一定临床应用和研究价值。 　　[关键词] 食管静脉曲张出血；内镜下套扎术；效果 　　[中图分类号] R575.2[文献标识码] A[文章编号] 1673-7210（2014）06（b）-0031-04 　　 　　The efficacy of combining endoscopic looping ligature with drug for esoph ageal varices bleeding 　　LI Li1 CHEN Jie1 LIU Chunyan1 ZHANG Jun1 LI Feifei2 　　1.Department of Gastroenterology, Huzhou Central Hospital, Zhejiang Province, Huzhou 313000, China; 2.Department of Gastroenterology, the Affiliated Hospital of Inner Mongolia Medical University, Inner Monggol Autonomous Region, Huhhot 010059, China 　　[Abstract] Objective To explore the efficacy of combining endoscopic looping ligature with drug to esophageal varices bleeding. Methods From October 2011 to October 2013 in Huzhou Central Hospital of Zhejiang Province, 124 patients with esophageal varices bleeding were randomly selected and these were divided into two groups according to random number table method, 62 cases were treated with endoscopic looping ligature combined routine hemostatic anti-inflammatory drugs as experiment group, such as Pantoprazole, somatostatin and Naphthalene, the control group were done with ordinary methods. The different of two groups on classification of bleeding, hemostatic effect and complications were analyzed. Results The different comparison of Child-Pugh for grading and bleeding rate, Child-Pugh C grade was obvious higher than Child-Pugh A and B grade with statistical significance (P 0.05). And bleeding of experiment group was 3.23%, which was less than the control group (19.35%); relapse