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心力衰竭的放射性核素显像评价.ppt
2-Year Cardiac Death and All-Cause Mortality Rates Versus H/MTwo-year cardiac death (A) and all-cause mortality (B) rates show progressive decline from 20% for heart/mediastinum ratio (H/M) 1.10 to 0% for H/M ≥1.80. * Cumulative Event Curves in Relation to BNP, LVEF, and H/MThere is a highly significant difference in primary event (A) and cardiac death rates (B) between subjects with B-type natriuretic peptide (BNP) below and above the median value of 140 ng/l. Addition of the heart/mediastinum ratio (H/M) (1.60 vs. ≥1.60) further stratifies subjects with high BNP (C, D). There is a highly significant difference in primary event (E) and cardiac death rates (F) between subjects divided at the median left ventricular ejection fraction (LVEF) of 29%. Addition of the H/M (1.60 vs. ≥1.60) further stratifies subjects in both LVEF groups (G, H). * * * * * * * HSV-ttk报告基因干细胞PET成像 18F-FHBG 18F-FDG Li Z, et al. Stem Cells. 2008;26:864-873. PLoS ONE. 2009;4:e8443. J Am Coll Cardiol. 2009;53:1229-40. Influence of intracoronary stem cell therapy on LVEF, infarct area, and FDG metabolism in PET study Before Tx After Tx Difference P Value LVEF, % 52?9 60?7 +15% 0.0001 Infarct area, % 27?8 19?9 -30% 0.0001 FDG-PET, % 43.8?8.0 50.5?11.6 +15% 0.012 Modified from Strauer et al. JACC Vol. 46, No. 9, 2005 Regeneration of Human Infarcted Heart Muscle by Intracoronary Autologous Bone Marrow Cell Transplantation in Chronic CAD: The IACT Study Strauer et al. JACC Vol. 46, No. 9, 2005 Dilated Cardiomyopathy Due to Doxorubicin/ Anthracycline Cardiotoxicity RNA is an ideal noninvasive tool to provide longitudinal quantitative assessment of LV function in patients receiving doxorubicin and other anthracyclines such as epirubicin. EF should be measured in all patients before receiving doxorubicin; those with pre-existing heart disease and/or LV dysfunction are at greater risk of congestive heart failure. * * * * * * * * * * * Nuclear cardiology offers an additional modality for assessing m
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