滋阴润肤方熏洗疗法及综合护理干预糖尿病皮肤瘙痒的研究及.docVIP

滋阴润肤方熏洗疗法及综合护理干预糖尿病皮肤瘙痒的研究及探讨 陆静波 沈永红 王璐 荣丽媛 马天 （上海中医药大学附属岳阳中西医结合医院,上海 200437） 摘要: 目的 探讨滋阴润肤方熏洗疗法治疗糖尿病皮肤瘙痒的临床疗效及综合护理干预措施的技术要点。方法 将60例患者随机分为治疗组27例和对照组33例；治疗组患者采用滋阴润肤方熏洗，对照组患者采用清水熏洗，如症状无缓解则加用止痒药物，2组患者都采取规范的综合护理干预措施，疗程10d。比较治疗前后2组患者的临床疗效（瘙痒VAS评分、皮损愈合时间及使用止痒药物的例次）、血清瘙痒介质指标（P物质、β-内啡肽及γ-干扰素）、血糖（空腹及餐后2h）及肾功能（肌酐、尿素氮）。结果 治疗后治疗组患者的VAS评分和皮损愈合时间均优于对照组（P＜0.05），治疗组患者使用止痒药物的例次少于对照组（P＜0.01）；2组患者治疗后血清P物质、β-内啡肽及γ-干扰素指标的比较差异有非常显著性（P＜0.01）；2组患者治疗后血清血糖、肌酐、尿素氮指标的比较差异无显著性（P＞0.05），不良反应轻微。结论 滋阴润肤方熏洗治疗糖尿病皮肤瘙痒的疗效优于清水熏洗治疗，规范的综合护理干预措施是提高疗效的重要保证。 关键词: 糖尿病；皮肤瘙痒；熏洗；滋阴润肤方；综合护理干预 Clinical Study of?Ziyinrunfu Herbal Fumigation to Patients with Diabetic Pruritus and Related Comprehensive Nursing Intervention Measures.(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437,China) Jing-bo LU, Yong-hong SHEN, Lu WANG, Li-yuan Rong ,Tian MA. Abstract: Objective To study the clinical efficiency of Ziyinrunfu herbal fumigation to patients with diabetic pruritus and related comprehensive nursing intervention measures. Methods 60 patients with diabetic pruritus were randomly divided into two groups:27 cases of treatment group and 33 cases of control group. Cases of treatment group were treated with Ziyinrunfu herbal fumigation and cases of control group were treated with water fumigation. Antipruritics would be used if symptoms were not relieved. Standardized comprehensive nursing intervention measures were taken in the two groups. The therapy course of both groups was 10 days. Clinical effect（Pruritus VAS score, days of skin lesion healing and cases of using antipruritics），serum itching index(substance P、β-EP and INF-γ), blood glucose (fasting and postprandial 2h) and kidney function index（Cr and BUN）were observed before and after treatment. Results Pruritus VAS score and days of skin lesion healing were superior to that in control group (P＜0.05 or ＜ 0.01). Cases of using antipruritics in the treatment group were le