考研资料:北京大学细胞生物学 第八章 细胞核-上幻灯片.pptVIP

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考研资料:北京大学细胞生物学 第八章 细胞核-上幻灯片.ppt

Nucleus and Chromosomes C. Nuclear pore complex (NPC) D. Molecules enter and exit the nucleus through nuclear pore complex Passive transport—passively diffuse Active transport NLS are present only in nuclear proteins A typical NLS contains several consecutive basic amino acids (the positively charged Aa: Lys, Arg) Nuclear import and export Nuclear import receptors bind NLS and Nucleoporins The Ran GTPase drives directional transport through NPC Nuclear export works like nuclear import, but in reverse hnRNP proteins contain a nuclear-export signal (NES) Refere

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