PRACTICE PATTERNS OF RADIOTHERAPY IN CERVIX 宫颈放射治疗的实践模式.pptVIP

PRACTICE PATTERNS OF RADIOTHERAPY IN CERVIX CANCER AMONG MEMBER GROUPS OF THE GYNECOLOGIC CANCER INTERGROUP (GCIG) D GAFFNEY1, A DU BOIS2, K NARAYAN3, N REED4, T TOITA5, S PIGNATA6, P BLAKE7, L PORTELANCE8, A SADOYZE9, R POTTER10, A COLOMBO11, M RANDALL12, MR MIRZA13, EL TRIMBLE14, 1RTOG, USA? 2AGO-OVAR, Germany? 3ANZGOG, Australia/New Zealand? 4EORTC, Scotland? 5JGOG, Japan? 6MITO, Italy? 7Royal Marsden Hospital, England? 8NCIC, Canada? 9SGCTG, Scotland? 10AGO-AUST, Austria 11MANGO, Italy 12GOG, USA 13NSGO, Scandinavia 14NCI, USA Methods Survey Developed Radiotherapy practice Indications Doses Fields Chemotherapy Brachytherapy 4 questionnaires per group 39 returned from 13 groups Descriptive statistics RT Doses Total Point A Doses: North America Compared to Other Cooperative Groups Type of Simulation for Definitive RT Size of Pelvic Field for Definitive RT IMRT in Definitive RT? Type of Chemotherapy for Definitive RT? Dosing of CDDP for Definitive RT (n=30) Adjuvant Chemo post Hysterectomy and Concurrent ChemoRT Intervene for a low Hemoglobin Type of Brachytherapy for Definitive RT Indications for Para-aortic RT Upper Border for Para-aortic RT Vaginal Brachytherapy post Hysterectomy 18 Rx’d to ? cm, 8 to Vag surface, 1 to one cm 23/25 recorded dose to bladder and rectum 23/27 used HDR For HDR Median dose: 17.5 Gy Median dpf: 6 Gy Conclusions Radiotherapy Practices among members of GCIG are similar in terms of doses and fields Concomitant chemotherapy is used by all groups with CDDP predominating There is no consensus on vaginal brachytherapy prescription Radiotherapy practices should not be a barrier to intergroup participation in clinical trials Acknowledgments Mason Schoenfeldt and Monica Bacon Executive Board of the GCIG Respondents Collegiality among all members * RTOG USA JGOG Japan MITO Italy EORTC ANZGOG Australia/New Zealand AGO-OVAR Germany MRC (NRCI) NCIC Canada AGO-AUST Austria SGCTG Scotland MANGO Italy NSGO Scandinavia GEICO Spain G