Substance Related Disorders University of Washington华盛顿大学物质相关疾病.pptVIP

* Cannabis CANNABIS Most commonly used illicit drug in America THC levels reach peak 10-30 min, lipid soluble; long half life of 50 hours Intoxication- Appetite and thirst increase Colors/ sounds/ tastes are clearer Increased confidence and euphoria Relaxation Increased libido Transient depression, anxiety, paranoia Tachycardia, dry mouth, conjunctival injection Slowed reaction time/ motor speed Impaired cognition Psychosis CANNABIS (cont.) Neuroadaptation CB1, CB2 cannabinoid receptors in brain/ body Coupled with G proteins and adenylate cyclase to CA c