心脏生理ppt课件.ppt

* * excitability autorhythmicity conductivity contractivity Electrophysiological characters Mechanical character Chapter 2: Cardiac Physiology 2.1 the Pump Function of Heart *Pulmonary circulation *systemic circulation Structure of the Heart External Ca initials the cardiac contraction *calcium-induced calcium release Contraction features of Heart Dependent to extracellular Ca All or None No complete tetanus *systolic phase (systole) 2.1.1 Cardiac Cycle Cardiac Cycle *diastolic phase(diastole) atrioventricular valve--open A. atrial systole (0.1 s) 2.1.2 the process of Cardiac Pumping 10~30% returned blood volume intra-auricular pressure intraventricular pressure atrioventricular valve semilunar valve B. ventricular systole *period of isovolumic contraction(0.02-0.03 s) ventricular myocardium close intraventricular pressure ventricle volume - *period of rapid ejection (0.11 s) *period of slow ejection (0.22 s) intraventricular pressureaortic pressure semilunar valve--open Volume--decrease intraventricular pressure--maximum intraventricular pressureaortic pressure 30% strike volume 70% strike volume C. ventricular diastole *period of isovolumic relaxation(0.03~0.06s) atrioventricular valve semilunar valve ventricular myocardium close intraventricular pressure ventricle volume - *period of rapid filling atrioventricular valve--open intra-auricular pressure intraventricular pressure *period of reduced filling C. Function of valve, ventricular and atrial contraction Atrioventricular pressure gradient Ventricular myocyte diastole systole ventricle-aortic pressure gradient atrioventricular valve semilunar valve atria ventricle aorta venous return↑ atrial contraction Ventricular filling volume↑ end-diastolic dimension↑ ventricular ejection↑ 2.1.3 Heart sound Mechanism A. Heart sound and phonocardiogram B. First and second heart sound Location to hear Physiological and clinical signi