多烯磷脂酰胆碱联合还原型谷胱甘肽注射液治疗肝功能异常疗效观察.docVIP

多烯磷脂酰胆碱联合还原型谷胱甘肽注射液治疗肝功能异常疗效观察 　　摘要：目的 观察多烯磷脂酰胆碱注射液联合还原型谷胱甘肽注射液治疗各种病因引起的肝损害疗效。方法 选择各种原因引起的肝功能损害患者119 例，随机分为治疗组和对照组。治疗组：给予多烯磷脂酰胆碱注射液465mg静滴，1次/d，还原型谷胱甘肽注射液 1.2g 静滴，1次/d。对照组：仅给予多烯磷脂酰胆碱注射液465mg静滴，1次/d。观察两组治疗前后肝功能及预后情况。结果 治疗14d后，治疗组患者症状体征改善情况优于对照组，治疗组显效及有效51 例（93.3%），对照组显效及有效34例（83.3%），治疗组肝功能损害恢复情况优于对照组，两组差异显著（P0.05）。结论 多烯磷脂酰胆碱明显改善肝功能损害和临床症状，疗效显著。 　　关键词：肝损害；还原型谷胱甘肽注射液；多烯磷脂酰胆碱注射液 　　Abstract：Objective To observe the clinical effect of Polyene Phosphatidylcholine injection combined with Reduced Glutathione for Injection on liver injury caused by different diseases.Methods 120 patients who suffered from liver injury were randomly divided into two groups： treatment group and control group. Treatment group：injected Polyene phosphatidylcholine injection 465 mg， once a day. injected Reduced Glutathione for Injection 1.2g， once a day. Control group： injected Polyene phosphatidylcholine injection 465 mg， once a day.；course of treatment was 14 days in two groups. The curative effect on liver function and prognosis of the two groups before and after treatment were observed. Results After 14-day treatment， patients symptoms of the treatment group improved more obviously than those of the control group， and 51 cases achieved excellent effects （93.3%） in the treatment group， while 34 cases achieved excellent effects （83.3%）. The treatment group was superior to the control group in reviving Liver Injury. There were significant difference among different groups（P0.05）. Conclusion Polyene phosphatidylcholine injection could obviously improve liver injury and clinical symptoms， the curative effect is remarkable. 　　Key words：Liver injury； Reduced Glutathione for Injection； Polyene phosphatidylcholine injection 　　近年来，随着人们物质生活不断提高，各种药物的广泛应用，肝功能损害患者也日益增多。本研究通过对3 年来治疗各种原因引起的肝功能损害患者的临床资料进行回顾分析，发现应用多烯磷脂酰胆碱注射液联合还原型谷胱甘肽注射液治疗肝功能损害疗效满意，现报道如下。 　　1 资料与方法 　　1.1一般资料 选择2013年1月～2015 年1月住院治疗的不同原因引起的肝功能损害患者120例。随机分为治疗组和对照组。治疗组：共60例，男35例，女25例，年龄20～65岁，平均年龄（43.2±6.81）岁，肝功能损害原因：慢性乙型病毒性肝炎引起32例，药物性肝功能