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Hepatitis B Virus
Hepatitis B Virus Huamin Wang 王华民 Department of Microbiology Immunology Hainan Medical College 2007 Statistics on HBV Most healthy adults (90%) who are infected will recover and develop protective antibodies against future hepatitis B infections 90% of infants and up to 50% of young children infected with hepatitis B will develop chronic infections. Hepatitis B In the World 2 billion people have been infected (1 out of 3 people). 400 million people are chronically infected. 10-30 million will become infected each year. An estimated 1 million people die each year from hepatitis B and its complications. Approximately 2 people die each minute from hepatitis B. Hepatitis B In the United States 12 million Americans have been infected (1 out of 20 people). More than one million people are chronically infected . Up to 100,000 new people will become infected each year. 5,000 people will die each year from hepatitis B and its complications. Approximately 1 health care worker dies each day from hepatitis B. Hepatitis B in China 1.3 billion people the worlds largest population of hepatitis B patients, with nearly half a million people dieing of the liver disease every year 120 million Chinese have tested positive for hepatitis B, which has become a severe public health problem in the country General Concepts Hepatitis = inflammation of the liver. six medically important viruses are commonly described as “hepatitis viruses”: HAV,HBV,HCV,HDV,HEV,HGV. Definitions for Hepatitises Acute(急性): Short term and/or severe. Chronic(慢性): Lingering or lasting - may or may not be severe Fulminant(爆发性): Developing quickly and lasting a short time, high mortality rate. Cirrhosis(硬化): Hardening: may be the result of infection or toxins (e.g. alcohol) Jaundice(黄疸): Yellowing of the skin, eyes, etc due to raised levels of bilirubin in the blood due to liver damage. Hepatocellular carcinoma(肝细胞癌): is closely associated with hepatitis B, and at least in some regions of
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