2013动物分子数量遗传学试卷.docVIP

2013-2014学年第一学期农学院研究生考试卷 赵新宇 权慧燕 姓名 年级 2013 专业 动物遗传育种与繁殖 课程 动物分子数量遗传学 任课教师 冯登侦 1 .Explain term (20 point ,per term 10 point ) 1.1 genome 1.2 Identity by descent 2. solve problem( 70 point ) 2.1 What is the gene struction and compostion ? ( 20 point ) 2.2 The following sequencing gel generated by the enzymatic extension method. ( 20 point ) ⑴. What is the sequence of the template of strand? ⑵. If the template for the DNA sequencing is the strand that resembles the mRNA, is this likely to be within an exon of a functional gene? Explain your answer. 2.3 Prove that for an autosomal locus, when the gene frequencies are different in males and females, the gene frequencies will be in equilibrium after a single generation of random mating .(20point) 2.4 What would be the heritability estimated from each of the following correlations or regressions, assuming that resemblance duo to environment or dominance was negligible? ( 20 point) (1) Regression of offspring on father =0.21 (2) Regression of offspring on father =0.27 (3) Correlation of full sibs =0.34 (4) Regression of offspring on mean of parents =0.32 (5) Correlation of half sibs =0.02 (6) Regression of female offspring on mother’s sister =0.03 （7）Regression of daughters on dams, within sires =0.09 2013-2014学年第一学期农学院研究生考试卷 李靖 张玲玲 姓名 年级 2013 专业 动物遗传育种与繁殖 课程 动物分子数量遗传学 任课教师 冯登侦 1 .Explain term (20 point ,per term 10 point ) 1.1 DNA clones 1.2 Polymorphism 2. solve problem( 80 point ) 2.1 What is the affect factors of DNA denaturation and Renaturation. ( 20point ) 2.2 Imagine you have cloned a 14.7kb piece of DNA , which contains restriction sites as show below. ( 20 point ) B E H B E B=BamH1 site, E=EcoR1 site 2 1.4 3.5 3 0.8 4 H=HindⅢ site Numbers under the segm