分子生物学（杨洋）第十一章 真核生物基因表达调控.pptVIP

Outline: TOPIC 1: Principles of Regulation in eukaryotes Topic 2: Transcription factors Topic 3: chromatin structure and its effect on transcription Topic 4: eukaryotic repressors TOPIC 1 Principles of Regulation in eukaryotes Gene Expression is Controlled by Regulatory Proteins (调控蛋白) Gene expression is very often controlled by Extracellular Signals, which are communicated to genes by regulatory proteins: Positive regulators or activators INCREASE the transcription Negative regulators or repressors DECREASE or ELIMINATE the transcription E