2 Xi s Gout hyperuricemia in chronic renal uric acid metabolism in rats.docVIP

 PAGE \* MERGEFORMAT 11 2 Xi s Gout hyperuricemia in chronic renal uric acid metabolism in rats Of: Wang Jin Rui Qi Xi Wang Yicheng Zhao Zhaolin the September [Abstract] Objective: To observe the effect of gout Ling Xi’s No. 2 time in the different treatment of chronic hyperuricemia nephropathy (Urate Nephropathy, UN uric acid metabolism in rats, and with the benefit cents compared gout medicine to explore the Chinese Xi s Gout 2, mechanisms of serum uric acid and its application. Methods: XI s Gout Treatment 2 UN rats were observed for 2 weeks and 5 weeks later, Blood uric acid (serum Uric Acid, sUA, Serum xanthine oxidase inhibitor (serum Xanthine Oxidase, sXOD, uric acid renal clearance (Renal Excretive Rate, RER, serum creatinine (sCr, and renal morphology. Results: Xi s Gout was significantly lower 2 largest UN Rat sUA, sCr role, can inhibit sXOD activity, increased RER. Conclusion: Xi s Gout sXOD 2 may inhibit the activity of two ways to reduce the increase in RER sUA. [Keywords:] XI 2 s Gout, uric acid metabolism, rat Abstract Objective: To observe the curative effect of XI’s Gout killer-2 (prescription of traditional Chinese medicine) on metabolism of uric acid in the experimental rats of Urate Nephropathy. Methods: XI’S Gout killer-2 was used to cure the experimental rats of Urate Nephropathy, and in the second week and fifth week after the treatment the levels of sXOD, sCr, sUA, RER were, respectively, measured. Results: XI’s Gout killer-2 could remarkably reduce sUA and sCr in UN rats, inhibit sXOD activity and increase RER. Conclusion: XI’s Gout killer-2 may reduce sUA by restraining sXOD activity and increasing RER. Key Words XI’s Gout killer-2; Metabolism of Uric Acid; Rats S Gout Xi Xi series of prescriptions is Professor of the September the crystallization of decades of clinical experience, to achieve a satisfactory clinical efficacy of the treatment. XI s Gout treatment of chronic uric acid nephropathy have been clinical repo