2-microglobulin in the diagnosis of diabetic nephropathy.docVIP

 PAGE \* MERGEFORMAT 8 2-microglobulin in the diagnosis of diabetic nephropathy [Abstract] Objective To investigate the serum 2 microglobulin (2 MG and urinary 2-microglobulin and type 2 diabetic nephropathy. Methods immunoturbidimetry detected 98 cases of type 2 diabetes patients and 38 healthy control group, serum and urine 2 MG, in 98 diabetic patients in 50 cases of early diabetic nephropathy (DN group, diabetes, 48 cases of kidney damage does not appear (NDN group. Results In diabetic nephropathy, serum and urine 2 MG and the control group were statistically significant differences between ( P lt;0.01, diabetes, kidney damage does not appear, compared with the control group, serum 2 microglobulin difference was not statistically significant (Pgt; 0.05, urinary 2-microglobulin difference was significant (P lt;0.05. Conclusion Serum and early diagnosis of urinary 2-microglobulin in the diagnosis of diabetic nephropathy has a good value. [Keywords:] 2 microglobulin, diabetic nephropathy, serum, urine Abstract: Objective To explore the correlation between serumal and urinary 2 microglobulin (2 MG) in patients with diabetic nephropathy. Methods Immunoturbidimetry was used to measure 2 MG in serum and urine from 98 patients with type 2 diabetes and 38 normal patients. Among 98 cases of diabetes, 50 cases were diabetic nephropathy while the other 40 cases were not.Results Serumal and urinary 2 MG were significantly elevated in patients with diabetic nephropathy compared with those in normal patients (P lt;0.01) No marked difference of serumal 2 MG was detected but significant differences of urinary 2 MG were found between non nephropathy diabetes and normal persons (P lt;0.05). Conclusion Measuring serumal and urinary 2 MG is valuable to the diagnosis of diabetic nephropathy. Keywords: 2 microglobulin; diabetic nephropathy; serum; urine Current 20% to 50% in patients with type 2 diabetes with diabetic nephropathy (diabetic nephropathy, DN), has bec