2300 were adults cerebrospinal fluid culture and drug resistance analysis of strains.docVIP

 PAGE \* MERGEFORMAT 19 2300 were adults cerebrospinal fluid culture and drug resistance analysis of strains 【Abstract】 Objective To summarize our hospital from January 2002 to June 2005 submission of the 2300 adults were CSF culture and drug sensitivity for the clinical diagnosis and treatment information. Methods used by the U.S. DADE Inc. Microscan Walkaway 40 automatic bacterial identification and antibiotic susceptibility analysis system for determination of bacterial identification and antimicrobial susceptibility. Results in 2300 were cerebrospinal fluid samples, 180 were detected in the number of positive (7.83%), including 144 bacteria (98 Gram-positive bacteria, Gram-negative bacteria 46), 26 fungi, 10 strains of Mycobacterium tuberculosis. Streptococcus and Enterococcus sensitive to penicillin, vancomycin against Gram-positive cocci have a high antibacterial activity; Gram-negative bacteria to commonly used drugs cefotaxime and ceftriaxone in the sensitivity of poor, carbapenem, aztreonam against gram-negative bacteria have good antibacterial activity; part of the meningitis caused by Mycobacterium tuberculosis and fungi. Conclusion to nosocomial infection in this group mainly meningitis, suggesting that clinicians should be based on the characteristics of patients with meningitis, personalized medicine and rational use of antibiotics. Keywords: Cerebrospinal fluid drug-resistant pathogens reported Analyses on the pathogens and their resistance to antibiotics ABSTRACT Objective To analyze the pathogenic results and drug resistance of bacteria isolated from 2300 cerebrospinal fluild specimens of adults from 2002 to 2005 so as to provide evidence for clinical diagnosis and therapy of meningitis. Methods The bacteria identification and the antimicrobial susceptibility were assayed by automatic bacteria culture device Microscan Walkaway 40 from DADE Co. Results The positive rate of pathogens was 7.83% (180/2300) from 2300 cere