263 cases of middle-aged patients with chronic kidney disease and proteinuria rhythm of blood pressure renal function impairment analysis of the relationship.docVIP

 PAGE \* MERGEFORMAT 5 263 cases of middle-aged patients with chronic kidney disease and proteinuria rhythm of blood pressure renal function impairment analysis of the relationship Authors: YU Rong-Qiang, Shen Kai-Yue, Zheng Yulin [Abstract] Objective To observe the middle-aged chronic kidney disease (CKD) in patients with dynamic changes of 24h blood pressure, and explore the circadian rhythm abnormalities with proteinuria and renal damage relations. Method of randomly selected hospital medicine in-patient and outpatient kidney 263 cases of middle-aged patients with CKD. All patients were 24h ambulatory blood pressure monitoring, ambulatory blood pressure monitoring (ABPM) using a portable ambulatory blood pressure monitoring instrument. 24h dynamic changes of blood pressure according to the patients were divided into normal circadian rhythm of blood pressure and 48 cases; circadian rhythm of blood pressure group of 215 cases of disappearance, of which nocturnal blood pressure greater than the group of 93 cases during the day. Group discussions in each group of urine microalbuminuria, 24h urinary protein and renal function in. The results of blood pressure circadian rhythm disappeared group, especially at night than daytime blood pressure and microalbuminuria group, 24h urinary protein was significantly higher than normal blood pressure circadian rhythm, and its impaired renal function, in serious condition. Conclusions In middle-aged patients with chronic kidney disease are prevalent in loss of circadian rhythm of blood pressure; apparent disappearance of circadian rhythm of blood pressure and chronic kidney disease, urinary albumin, 24h urine protein, kidney damage related to the degree. [Keywords:] chronic kidney disease; ambulatory blood pressure monitoring; Circadian rhythm; proteinuria; renal function [Abstract] Objective To observe the change of 24-hour blood pressure and explore the relation between abnormality of circadian blood pressure rhythm, a