37 superfine quality standard of.docVIP

 PAGE \* MERGEFORMAT 17 37 superfine quality standard of 【Abstract】 Objective To establish a 37 superfine quality standards. Thin Layer Chromatography 37; the use of laser particle detector for detection of the particle size; HPLC determination of 37 saponins in 37 superfine R1, Ginsenoside Rg1, Ginsenoside Rb1 content. The results of TLC spots were clear patterns can be identified with the corresponding 37 spots; 37 superfine powder, the median diameter at 15 μm below; Notoginsenoside R1 in the range of 0.535 ~ 3.210 μg good linear relationship (r = 1.000), The average recovery of 103.08%, RSD = 2.80%; ginsenoside Rg1 in the range of 2.225 ~ 13.350 μg good linear relationship (r = 1.000), average recovery was 100. 33%, RSD = 2.29%; ginsenoside Rb1 in the 2.205 ~ 13.230 μg range a good linear relationship (r = 1.000), average recovery was 101.00%, RSD = 1.43%. CONCLUSION The method is simple, accurate, reproducible and can be used for quality control of 37 superfine Keywords: 37 ultrafine particle thin-layer chromatography quality standards for high-performance liquid Abstract: ObjectiveTo develop a quality standard for super micropowder of notoginseng.Methods Qualitative analysis of micropowder of notoginseng was carried out by TLC. The particle diameter was detected with laser scattering particle size distribution anaslyzer. An RP - HPLC method was used for the content determination of the Notoginsensode R1, ginsenoside Rg1, ginsenoside Rb1. ResultsThe chromatographic spots of micropowder of notoginseng were identified without the interference of negative control. Micropowder of particle average diameter was below 15μm. Notoginsensode R1 had a good linearity in the range of 0.535 ~ 3.210 μg (r = 1.000), and the average recovery was 103.08% with RSD of 2.80%. Ginsenoside Rg1 had a good linearity in the range of 2.225 ~ 13.350 μg (r = 1.000), and the average recovery was 100.33% with RSD of 2.29 %. Ginsenoside Rb1 had a good linearity in the r