4 County of Shanxi Province the environment on the risk factors of cleft lip and palate.docVIP

 PAGE \* MERGEFORMAT 15 4 County of Shanxi Province the environment on the risk factors of cleft lip and palate Of: Meng Li Zhiwen Ren Aiguo Zhang Le Liu Ye Rongwei [Abstract] Objective To screen the high incidence of cleft lip and palate birth defects in Shanxi province occurred in a variety of environmental risk factors for in-depth study provides clues to the cause. Methods A population-based case-control study of birth defects. Case group in January 2003 to 2006 on December 4 in the County of Shanxi Province, 96 cases detected in children with cleft lip and palate, were investigated for the same period 680 non-visible surface of normal infant birth defects. in women within 1 week after birth, through face to face method of investigation, collection of women’s In general, pregnancy before and after the lifestyle, diet, living conditions and other information. be the single factor analysis, screening of possible risk factors; will have a statistically significant factors included in multivariate non-conditional Logistic model. using the odds ratio (OR) risk estimate, and calculate 95% confidence interval (95% CI). logisitic multivariate regression analysis results showed that cold before and after pregnancy, high fever (OR = 4.6, 95% CI: 2.6 ~ 8.3), taking anti-inflammatory class drugs (OR = 7.5, 95% CI: 1.8 ~ 31.5), passive smoking per weekgt; = 1 (OR = 1.8, 95% CI: 1.0 ~ 3.0), weekly drinking winegt; = 1 (OR = 6.3 , 95% CI: 1.1 ~ 35.3), exposure to toxic substances (OR = 11.8, 95% CI: 1.2 ~ 117.3), longer time noise exposure (OR = 3.0, 95% CI: 1.2 ~ 7.4), meat lt;1 time / week (OR = 1.8, 95% CI: 1.1 ~ 3.1) and the related risk of cleft lip and palate occur. Conclusion of pregnancy before and after a cold or fever, taking anti-inflammatory drugs, smoking, drinking liquor, contact toxic chemicals, noise exposure and longer low frequency of meat consumption may be risk factors for cleft lip and palate in Shanxi Province. these factors through health educ