6 years in our hospital clinical application of hypoglycemic drug analysis.docVIP

 PAGE \* MERGEFORMAT 9 6 years in our hospital clinical application of hypoglycemic drug analysis Of: Liu Ying, Feng Huai-Zhi, Li Hongbin, Zhang Deyun, Lu Haibo [Keywords:] diabetes mellitus; hypoglycemic agents; DDDs; DUI Diabetes is not because the body can not produce or properly use insulin due to common disease, systemic metabolic and endocrine diseases. Diabetes can cause many acute and chronic complications, a serious threat to people’s health and life, is now become known worldwide than cancer, cardiovascular and cerebrovascular diseases threatening human health and life outside of the “third killer” [1]. In order to better guide clinical application of hypoglycemic agents, we apply the military hospital, “Army Word One “computer management system, to April 1, 2003 ~ April 30, 2009 1838 cases treated in hospital have diabetes drug use for statistical analysis. 1 Materials and Methods 1.1 Source 1838 cases of diabetes-related hospitalization data sources Information Center hospital room. Which accounted for 50.05% male 920; female 918 cases accounted for 49.95%. 1.2 Methods defined daily dose recommended by WHO (DDD) analysis, by lt;”China Pharmacopoeia Clinical Guide to thegt;” -2005 Edition [2], ““ A New Drug Studiesgt;gt; version 15 [3], “lt;useful drugs Manualgt;gt; Version 4 [4], “lt;Clinical pharmacology of General Practicegt;gt; [5],” lt;21 for fine clinical use mustgt;gt; [6] gathers related drugs and dosage, and reference section package insert, set the value of the drugs DDD. calculate DDDs (DDDs, DDDs = total dosage / drug DDD value [7], and sort, as a measure of drug use frequency, the greater the value that the greater selectivity of the drug in patients; the contrary, selective smaller (decrease). application chodse’s drug utilization index (DUI, DUI = DDDs / total days of medication) [8], to determine the reasonableness of physician medication , DUI lt;1 is reasonable, and otherwise unreasonable. application of daily medi