A major cause of rheumatoid arthritis of.docVIP

 PAGE \* MERGEFORMAT 7 A major cause of rheumatoid arthritis of [Keywords:] rheumatoid arthritis Rheumatoid arthritis (RAI) is a mainly involving the peripheral joints of multi-systemic inflammatory autoimmune disease whose main characteristic of symmetry, surrounded by a number of chronic inflammatory joint disease, clinical manifestations involved joint pain, swelling and functional decline in disease was sustained, repeated attack the process [1]. RA disease throughout the world [4], China is a big country the incidence of rheumatism, rheumatoid patients is only as high as 20 million people, and one-tenth of a severe illness. Therefore, RA is a frequently-occurring disease, common diseases, is also a disability a higher disease must draw our attention. RA may not be a single disease, but a multi-factor caused by the syndrome [3]. In order to effectively prevent them and reduce the incidence of RA, therefore this paper with the pathogenesis of rheumatoid arthritis to explore the main factors for reference. An infection of the factors 1.1 and the relationship between the virus [3] RA patients to EB virus nuclear antigen (EBV-NA), early antigen, shell membrane antigen (VCA) antibodies was significantly higher than normal, EBVNA antigen and the molecular weight of 62kD in the cytoplasm of synovial membrane antigens cross-reactivity. Recent reports VCA antigens and immunoglobulin Fc segment has cross-reaction, presumably with the RF generated mechanisms. With the virus, similar to RA-1 virus can be detected in RA patients. To newborn rats inoculated RA-1 virus, neurological abnormalities occurred in the same time, can cause limb arthritis. HTLV-1 can cause adult HTLV-1 associated with arthritis. The HTLV-1 gene transfer into mice, that occur in mice with chronic proliferative synovitis. This further illustrates that the pathogenesis of the virus and arthritis. 1.2 the relationship between bacterial infection and bacteria can cause aseptic arthritis. In expe