About remifentanil and isoflurane induced hypotension in neurosurgery surgery.docVIP

 PAGE \* MERGEFORMAT 9 About remifentanil and isoflurane induced hypotension in neurosurgery surgery [Abstract] Objective: Charui fentanyl and isoflurane in neurosurgery Bank of controlled hypotension. Methods: controlled hypotension for elective surgery. 50 patients were randomly divided into the remifentanil group (R group) and sodium nitroprusside group (S group), 25 patients in each group. R group: to 0.2μg / (kgpmin) rate of remifentanil began to give each increased every 30s 0.05μg / (kgpmin) until it reaches the target blood pressure; S group: from 1μg / (kgpmin) rate began to give sodium nitroprusside, increased every 30s 0.5μg / (kgpmin) until it reaches the target blood pressure. mean arterial pressure (MAP ) decreased to baseline of 60% to 70% as the goal blood pressure. recorded before anesthesia (T0), before hypotension (T1), controlled hypotension after 5min (T2), controlled hypotension after 30min (T3 ), controlled hypotension after 20min (T4), MAP, HR, CVP and surgeon satisfaction. Results: S T2 ~ T4 in the HR group compared with T0 and T1 increased; R T2 ~ T4 in the HR group compared with T0 and T1 slower than the S group of the HR slow T2 ~ T4; S group T4 of MAP, CVP higher than the T1, T4 are higher than the R group of MAP, CVP (P lt;0.05). R group, bleeding was less than S group (P lt;0.05), surgeon of the R group, satisfaction with the operative field higher than the S group (P lt;0.05). Conclusion: remifentanil and isoflurane induced hypotension in neurosurgery in the surgical process smooth, and neurosurgery to provide for a clearer operative field. [Keywords:] neurosurgery; Buck; Controlled / methods; Fentanyl / therapeutic use; Isoflurane / therapeutic use Remifentanil is a new μ-opioid receptor agonist, a rapid onset, short half-life, and shared use of general anesthetics may lower blood pressure, slowing heart rate. To understand the remifentanil and isoflurane can Bank of China in neurosurgery operations to meet the needs o