Acupuncture Effect of DSS treatment of Alzheimers Disease Mechanism.docVIP

 PAGE \* MERGEFORMAT 22 Acupuncture Effect of DSS treatment of Alzheimer’s Disease Mechanism Authors: LI Zhong-ren, Shen Hong Mei, Mu Yan-Yun, Ouyang Qi, Ma Cheng [Abstract] Objective To explore the clinical acupuncture Effect of DSS (DGSYS) treatment of Alzheimer’s disease, the possible mechanism. Methods intraperitoneal injection drug scopolamine or sodium nitrite, or with quinine acid damage to the brain occurs in rat hippocampal CA1 area induced memory barrier, resulting in different types of rats ‘dementia’ model, the control observation of acupuncture, acupuncture DGSYS, DGSYS and NM on the function of memory disorders, and memory-related changes in parameters of experimental index. Results Acupuncture DGSYS mechanism of anti-dementia therapy may be related to regulating the brain excitatory amino acid Glu energy and cholinergic neurotransmitter function and improve the in vivo antioxidant capacity of the system, such as improving SOD / LPO content and nitric oxide / nitric oxide synthase activity ratio is related to their coordinating role in promoting and hippocampal CA1 area of the brain damage of dementia model of LTP enhanced the recovery of learning and memory in rats, thereby improving the symptoms of dementia. Conclusions Acupuncture plus DGSYS therapy AD dementia and to improve learning and memory in the role of the exact scientific basis, it is worth clinical application. [Keywords:] acupuncture Effect of DSS modeling Alzheimer’s disease dementia neurotransmitter antioxidant long-term potentiation The studies on mechanism of Alzheimer’s disease by the acupuncture treatment combined with Danggui Shaoyao San of TCM [Abstract] Objective To explore into the probable mechanism of Alzheimer’s disease (AD) by the acupuncture treatment combined with DGSYS of TCM.Methods Three kinds of model rats with dysmnesia which were made by injected into drug of scopolamine or NaNo2 in the abdomen separately and injured at the hippocampal CA1 in brian by drug