Adult male serum alkaline phosphatase activity to reduce the main clinical significance of.docVIP

 PAGE \* MERGEFORMAT 7 Adult male serum alkaline phosphatase activity to reduce the main clinical significance of Author: Zhu 1 Li Fukun Sun Yan Wang Jingyang [Abstract] Objective: To further explore the cause of the reasons for lower serum alkaline phosphatase activity. Methods: From 2001 to 2005 with AMP-buffer method of alkaline phosphatase activity assay of a total of 2568 cases. 126 cases in which lower than normal, 88 cases were patients, 83 patients were male. Results: Patients with severe kidney disease and renal failure associated with accounting for 365%, malnutrition, accounting for 18% of patients, magnesium and the lack of patients accounted for 88%, 48% in patients with hypothyroidism, severe anemia, 3%, the remaining 24 cases (299% ) is not reduced and the serum ALP activity clearly related to symptoms. Conclusion: Serum ALP activity decreased mainly seen in severe chronic nephritis and was accompanied by renal failure, malnutrition and thyroid dysfunction that magnesium deficiency, severe anemia. Increase or decrease in serum ALP activity are important. [Keywords:] alkaline phosphatase, liver cirrhosis, hypothyroidism ALP (Alkaline phosphatase, ALP) is also known as acid phosphate ester hydrolase from the bone cells to bones and teeth, kidneys and liver are more content. The clinical focus on the ALP activity is usually higher in disease research, little attention to clinical disease and reduced ALP activity relationship. Therefore, we proceed to study the clinical significance of reduced ALP activity. 1 Materials and methods 11 instruments: Hitachi 7600 automatic biochemical analyzer. 12 Reagents: from Shanghai Shenergy - Desai diagnostic technology Limited. (1) reagent Ⅰ : 16mmol / L p-nitrophenyl phosphate disodium. (2) reagent Ⅱ : 2 - amino--2 - methyl -1 - propanol buffer, the concentration of 09mmol / L; pH102; MgCl2 concentration of 10mmol / L. 13 Determination method and reaction principle: The International Federation of Clinic