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PAGE \* MERGEFORMAT 11
Adverse effects of antibiotics and countermeasures
[Abstract] infectious diseases continue the development of diagnostic techniques, treatment of more and more out of the question, how to solve infection control problems and a growing number of emerging antimicrobial resistance problems. We should have a clinician antimicrobial spectrum of antibiotics, adverse reactions, to seek countermeasures.
[Keywords:] antibiotics; adverse reaction; Strategy
With the progress in antimicrobial therapy of infectious diseases so that great changes have taken place, the incidence rate decreased significantly. But because of the adverse reactions of antibiotics and the number of iatrogenic diseases. Thus, it should take preventive measures. The following from the talk about different aspects of bacteria and the body side effects of antimicrobial agents and their countermeasures.
1 Bacterial aspects
1.1 The emergence of multiple drug resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus Candida albicans [1] and Mycobacterium Shigella bacteria resistance to the most serious problems. long-term use of antibiotics, the bacteria is easy to produce -lactamase, its third-generation cephalosporin -lactam and carbapenem class of antibiotics effective against the other, such as penicillin , no enzyme inhibitors were obvious cephalosporin resistance [2], while Escherichia coli and Shigella bacteria is due to multiple drug resistance R plasmid conjugal transfer [3]. sepsis caused by these bacteria and therefore increasingly compelling.
Solution: correct and rational use of antimicrobial drugs. Must be applied, on pyogenic bacteria resistant bacteria can be sensitive to new antimicrobial agents, the use of combination therapy to prevent emergence of drug resistance, which has been in the treatment of tuberculosis was confirmed.
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