Angelica Extraction Process.docVIP

 PAGE \* MERGEFORMAT 5 Angelica Extraction Process Author: Li Ling, Li Zulun, Yu-Xin, Yuan Yu [Abstract] Objective To screen the optimum conditions for ethanol extract of Angelica. Method first used single-factor experiments to Angelica coumarins content in order to evaluate indicators, to conduct the study Angelica smash, followed by the use of L9 (34) orthogonal experiment, select the ethanol concentration, extraction time, extraction times, ethanol use four factors, set up three levels of each factor in order to flood out the volume (dry paste rate), Angelica coumarins content indicators, orthogonal experiment, pairs of Angelica ethanol extraction process to conduct investigations. Angelica ethanol extract optimum results as follows: take Angelica crushing, over 20 mesh sieve, plus 8 times the amount of 75% ethanol, extracted three times, 3 h / times. Conclusion The extraction process using high efficiency, good stability, industrial production for Angelica extract provides the optimum conditions for reference. [Keywords:] Angelica ethanol extract orthogonal Angelica Angelica Umbelliferae of Angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f. or Hang Angelica Angelica dahurica (Fisch.ex Hoffm) Benth.et Hook.f.var.formosana (Boiss.) Shan et Yuan dry root, with a casual air dehumidification, Tongqiao pain, swelling the effect of removing the abscess, mainly for cold headache, Mei Leng bone pain, stuffy nose, nasosinusitis, toothache, leucorrhea abnormalities, sore throat [1] . Modern research shows that the analgesic active ingredients are mainly coumarin substances: if Imperatorin, Isoimperatorin so. Accordingly, in the experiment using L9 (34) orthogonal design experiments, select the impact of ethanol extraction of Angelica four important factors, namely, ethanol concentration, extraction time, extraction times, alcohol consumption, set up three levels of each factor in order to Flooding out the volume (dry paste rate), Angelica coumarin content of the