Application sheets and irregular diet thyroid liver depression syndrome established rat model of.docVIP

 PAGE \* MERGEFORMAT 15 Application sheets and irregular diet thyroid liver depression syndrome established rat model of Of: Liu Surong, Cao Jin, Wuxi Li, Wang Zhiyong, Wang Min, Yan-Qiong [Abstract] Objective To establish a rat model of liver depression syndrome medicine, a new modeling method. Methods were fed with thyroid hormone tablets, irregular diet feeding method, the behavior changes of rats to measure rectal temperature in rats and was detected by sandwich ELISA in plasma serotonin (5 hydroxytryptamine, 5 HT), norepinephrine (norepinephrine, NE), epinephrine (epinephrine, E) levels and the impact on the content of Xiaoyaosan. Results Liver Model group and Xiaoyaosan group rats were 28 days of modeling the heart and liver appeared Huo typical of the disease, body temperature were increased, compared with the control group significantly (P lt;0.05), in 44 of modeling days, the liver model group, plasma 5 HT, NE, E level was significantly higher than before (P lt;0.05 or P lt;0.01), and NE, E higher than Xiaoyaosan group (P lt;0.01 and P lt;0.05 ), at 56 days of modeling a typical liver model group, the behavioral characteristics of depression Syndrome, Xiaoyaosan group was lower than plasma 5 HT liver model group (P lt;0.01). Conclusion thyroxine tablets and irregular diet method established rat model of liver depression syndrome meet the basic features of traditional Chinese medicine depression Syndrome. [Keywords:] depression Syndrome, rat model, Xiaoyaosan ABSTRACT: Objective To study a new method of establishing the rat model of liver depression syndrome. Methods We adopted gaster poured with thyroxine tablet and fully poorly feeding food in turn, observed the praxiological changes of rats, measured the temperature in anus, chose the sandwich ELISA to detect the level change of 5 hydroxytryptamine (5 HT), norepinephrine (NE), epinephrine (E) in plasma and the effect of Xiaoyao Powder on change of their contents. Results From the 28th day