Application of traditional Chinese medicine during pregnancy and lactation and risk control.docVIP

 PAGE \* MERGEFORMAT 11 Application of traditional Chinese medicine during pregnancy and lactation and risk control [Abstract] pregnancy and breast-feeding is safe and effective application of traditional Chinese medicine related to the health of the fetus and suckling, should strengthen the application of risk management of Chinese medicine, standard clinical treatment. [Keywords:] Chinese drug risk during pregnancy lactation Pregnancy and lactation is women’s specific physiological stage, more than half the women in this period due to illness and taking medication or are receiving drug treatment during pregnancy. Many patients and even health care workers safe non-toxic one-sided view of Chinese medicine, Chinese medicine toxicity and adverse reactions is not enough emphasis, the objective, causing the blind use of traditional Chinese medicine for pregnant women and nursing mothers, offspring safety hazard. how pregnancy and lactation to maximize benefits while controlling medicine therapy on the risk of fetal and suckling of the medication, as this is A clinical pharmacist should be concerned about and in-depth study. 1 pharmacokinetic characteristics of the fetus during pregnancy Almost all drugs can be transferred to the fetus through the placental barrier in vivo, after 12 weeks of pregnancy, drugs can be swallowed by the fetus into the fetal blood circulation. Fetal plasma albumin levels less than adults with high free-type drugs, pharmacological activity strong. And fetal liver drug metabolizing enzyme poor activity, drug metabolism is low, blood concentrations of certain drugs in the fetus than the mother of one to several times after the metabolism of certain drugs also have toxic degradation products. fetal glomerular filtration rate, excretion of drugs and slow degradation, easy to accumulate in the fetal damage. Therefore, the fetus is more sensitive to the drug, some adverse effects on the mother is not a drug will cause fet