Astemizole (Astemizole) clinical safety evaluation of literature.docVIP

 PAGE \* MERGEFORMAT 10 Astemizole (Astemizole) clinical safety evaluation of literature [Keywords:] National Drug National Adverse Drug Reaction Monitoring Center in July 2002 in the ‘rate of adverse drug reactions bulletin’ second phase of the dissemination of related ‘Astemizole (tablets) adverse reactions and drug interactions’ in communications. The circular According to China’s Adverse Drug Reaction Monitoring Center, a database of information and the international community about the safety of astemizole evaluation data, suggesting that a suspected adverse reaction to allergy and cardiovascular system response based. China’s relevant Astemizole the release of the communication of information caused by China’s pharmaceutical industry and the general public attention. To fully understand the clinical drug astemizole security, special conducting clinical safety of astemizole in the system literature investigation, with a view to our country, Adverse Drug Reactions Monitoring Center data for pairs of Astemizole the clinical use of drugs in our country provide the basis for safety evaluation of . A general 1.1 Astemizole clinical indications and the main safety issues Astemizole (Astemizole) Department of second-generation histamine H1 receptor antagonist, has absorbed quickly, the role of histamine receptor antagonists strong, lasted longer, while the central role of inhibition and anticholinergic pharmacological characteristics of the weak. Astemizole Tablets by Janssen Pharmaceutica Inc. (Janssen Pharmaceutical) the production, trade names Astemizole (Hismanal). The product is available in the UK in 1983, 1988 in the United States, China and Germany in 1989, is listed in Germany, has been included in the non-prescription drugs. Since then the product over a hundred countries in the global market, and widely used. Astemizole listed on the initial indications, including perennial or seasonal allergic rhinitis, allergic conjunctivitis, chronic urticaria