Atrial fibrillation and interleukin6 relations.docVIP

 PAGE \* MERGEFORMAT 10 Atrial fibrillation and interleukin6 relations Of: New Tang Zheng Jinguo high Shuping Ge Lijun Tao He Yonghui Pan Min Shi Guiliang [Abstract] Objective: To evaluate the atrial fibrillation (AF) and interleukin 6 (IL 6) relationship. Methods: 127 patients with AF and 109 patients with sinus rhythm in patients with human serum IL 6, blood lipid levels and echocardiography left atrial diameter. Comparison of the differences between the groups index. Results: AF of the left atrial diameter (53.81 + -8.93) mm was significantly higher than the sinus rhythm group (38.95 + -3.11) mm, the difference was significant (P lt; 0.01). AF group IL 6 levels (524.07 + -142.98) pg / ml was significantly higher than the sinus rhythm group (268.75 + -115.43) pg / ml, the difference was significant (P lt;0.01). AF serum IL 6 level and left atrial diameter was positive correlation (r = 0.707, P lt;0.01). Logistic regression multivariate analysis showed that IL 6, left atrial diameter as an independent risk factor for AF onset. Conclusion: IL 6 levels and the pathogenesis of AF . [Keywords:] Atrial fibrillation; interleukin-6; inflammation [Abstract] Objective: To explore the relationship between atrial fibrillation (AF) and interleukin 6 (IL 6). Methods: Serum levels of IL 6 and lipid parameters in 127 AF patients and 109 controls with sinus rhythm were measured. The left atrial diameter (LAD) was also detected by echocardiography. Results: LAD in AF group (53.81 + -8.93) mm was statistically higher than that in sinus rhythm group (38.95 + -3.11) mm. And also, the IL 6 levels in AF group ( 524.07 + -142.98) pg / ml was statistically higher than that in sinus rhythm group (268.75 + -115.43) pg / ml. IL 6 serum level and LAD in AF group was linear correlation (r = 0.707, P lt;0.01). Logistic regression analysis revealed that IL 6 and LAD were independent risk factors of AF. Conclusion: IL 6 was associated with AF. [Keywords:] atrial fibrillation;