Bone marrow mononuclear cells and bone marrow stromal cells compare the efficacy of treatment of femoral head necrosis.docVIP

 PAGE \* MERGEFORMAT 20 Bone marrow mononuclear cells and bone marrow stromal cells compare the efficacy of treatment of femoral head necrosis [Abstract] Objective bone marrow mononuclear cells were observed in bovine cancellous bone, bone marrow stromal cells implanted in bovine cancellous bone and separate rabbit xenogeneic bone repair of femoral head results, and compare them to determine bone marrow mononuclear whether the cells as repair of femoral head necrosis. Methods 23 New Zealand white rabbits, frozen with liquid nitrogen method, the establishment of bilateral femoral head necrosis, necrosis of the femoral head 45 of which were obtained, were randomly assigned to the control group, experiment 1 group, experimental group 2. 15 in each femoral head. the control group after core decompression alone xenogeneic bone implants, experimental group 1 after core decompression combined with bone marrow stromal cells implanted xenogeneic bone, experimental Group 2 after the implantation of composite core decompression and bone marrow mononuclear cells of bone xenograft. 2,4,8 weeks after surgery, X-ray examination were performed, Masson stain, and neovascularization area percentage and new trabecular bone volume percentage of the statistical analysis. The results included 23 New Zealand white rabbits were the result analysis. X ray and experimental 1,2-Masson staining showed the same effect repaired group were better than the control group. neovascularization after new bone area percentage and the femoral head volume fraction compared to the same period the experimental group was better than the control group, and statistically significant difference. In addition to the experimental group 1,2 2,4 weeks the percentage of vessel area, the rest had no significant difference. Conclusion Bone marrow mononuclear cells do have to repair the effects of femoral head necrosis and bone marrow stromal stem cells to repair similar effect. [Keywords:] bone marrow mononu