Children with allergic antibodies against vascular endothelial cells sense.docVIP

 PAGE \* MERGEFORMAT 8 Children with allergic antibodies against vascular endothelial cells sense Of: Tangxue Qing, Sun Wenping, Zou Ziying, Liu Wenbin, Wang Taisen, FORCES, PROCEEDINGS OF [Abstract] Objective To study the anti-vascular endothelial cell antibodies (AECA in Henoch-Schonlein purpura (HSP pathogenesis and clinical value and performance relationship. Ways determined by indirect immunofluorescence 49 cases of HSP patients and 41 healthy control patients in vivo positive rate. Results HSP group AECA positive rate (53.1% significantly higher (0%, a significant difference between the two compared, including IgA-AECA positive rate of detection of IgG-AECA, AECA positive nephritis group higher than non-nephritis group, there was significant difference between the two. Conclusions AECA in the pathogenesis of HSP, can reflect the kidneys are involved. [Keywords:] Purpura, allergic, anti-vascular endothelial cell antibodies, immune globulin [Abstract] Objective To study the roles of anti-endothelial cells antibodies (AECA in the pathogenesis and clinical manifestation of purpura.Methods AECA were examined by indirect immuofluorescenc (IIF between 49 patients of henoch-schonlein purpura and 41 controls.Results The positive rate of AECA in HSP was significantly higher than that in control; IgA-AECA positive rate was higher than that of IgG-AECA; AECA positive rate in HSPN was higher than that of without nephritis group.Conclusion AECA may participate in the pathogenesis of HSP, and are valuable in the diagnosis of henoch-schonlein purpura with renal complication. [Keywords:] henoch-schonlein purpura; anti-endothelial cells antibodies (AECA; immunoglobulin Allergic purpura (henoch-schonlein purpura, HSP is a small vessel disease as the main systemic vasculitis, the pathogenesis is not clear, in recent years, studies suggest that immune injury to play a role in the pathogenesis of this article by indirect immunofluorescence Determination of an