Children with lupus nephritis clinical and pathological features.docVIP

 PAGE \* MERGEFORMAT 13 Children with lupus nephritis clinical and pathological features Of: Zhuang Jie Qiu, Zheng Wenjie, Yang Qing, YANG Yu true, Lin Yanhong, Chen Xiaoying, Li Xiao Lu, Lin Ruixia [Abstract] Objective?: In children with lupus nephritis (lupus wephritis, LN) clinical performance and the relationship between renal pathology. Methods: We retrospectively analyzed 54 cases of LN in children with clinical manifestations, laboratory data and renal pathology . Results: 54 patients with LN, male: female was 1:2.6, the clinical manifestations of renal damage as first accounted for 27.8%, the most common clinical type of nephrotic syndrome (68.5%), type of renal pathology in type most ( 44.4%), followed by type (24.1%) and type (accounting for 16.7%); type LN and more with nephrotic syndrome (29.6%), but 4 patients (7.4%) showed only mild urinary abnormalities, hypertension and renal insufficiency highest incidence; 3 cases (5.5%) clinical pathology has nephrotic syndrome type . Conclusions: The clinical manifestations of LN and certain pathological changes related but not identical, clinical diagnosis should be comprehensive clinical, immunological parameters and early clear positive renal biopsy renal pathology. [Keywords:] children; lupus nephritis; renal biopsy; pathology Systemic lupus erythematosus (systemic lupus erythema-tosus, SLE) is a system involving multiple systemic autoimmune diseases, including lupus nephritis (lupus wephritis, LN) is one of the main complications.’s Early clear LN LN pathology in understanding the severity and guide rational treatment is extremely important, but also improve the prognosis of SLE patients, the key to reducing mortality. retrospective analysis of 13 years in our hospital treated 54 cases of children with LN clinical and pathological features, aims to pediatrician for children in raising awareness of LN. 1?? Data and Methods 1.1?? General information?? Collected in December 1995 -2008