Chinese medicine to prevent steroid-induced femoral head necrosis intravascular coagulation study.docVIP
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Chinese medicine to prevent steroid-induced femoral head necrosis intravascular coagulation study
[Abstract] steroid-induced femoral head necrosis (SANFH) intravascular coagulation mechanism are mainly four areas, SANFH induced prothrombotic state, SANFH changes caused by changes in blood flow, SANFH condensate caused by abnormal blood lipid and fiber, SANFH caused by an oxide changes in nitrogen and endothelin levels. From the dialectical point of view of Chinese medicine can improve SANFH thrombosis caused by pre-state variable changes in blood flow, reducing blood fat, adjust the fiber coagulation abnormalities, increased NO, lower ET content.
[Keywords:] Femoral head necrosis; steroid-induced; intravascular coagulation; traditional Chinese medicine
Steroid-induced avascular necrosis (Steraid induced Arascular Necrosis of Femoral Head, SANFH) is the adrenal cortex steroids necrosis femoral head short. Since the first reported in 1957, the use of corticosteroid-induced femoral head necrosis has been, due to organ transplantation, systemic lupus erythematosus, rheumatoid arthritis and other diseases, the use of glucocorticoids, leading to increased cases of femoral head necrosis [1]. This nearest few years, Chinese medicine to prevent intravascular coagulation mechanism SANFH study are outlined below.
A traditional Chinese medicine can improve SANFH prothrombotic state caused by
Prothrombotic state refers to the vascular endothelial cells, platelets, blood coagulation, blood coagulation and fibrinolysis systems and other related blood clotting factors, or blood rheology due to pathological changes occur for various reasons, which induce the pathological process of thrombosis or disease state [ 2]. SANFH intravascular coagulation with thrombosis of the conditions: slow blood flow, increased blood coagulation, vascular endothelial cell damage. Han Dong et al [3] with endotoxin plus hormone with rabbit modeling, the results appear in
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