Chromosome of 2 308 patients.docVIP

 PAGE \* MERGEFORMAT 6 Chromosome of 2 308 patients [Keywords:] Chromosome Analysis With the development of medical science, many diseases can be effectively controlled, hereditary and congenital diseases are increasingly becoming a serious hazard to human health and life is difficult to cure chronic disease. Research work carried out prenatal and postnatal care is to prevent an important measure of genetic and congenital diseases. Therefore, premarital and preconception care, prenatal diagnosis was widespread concern about the rapid development of genetics and technology, in order to control population, and improve population quality, and to achieve health care strategies, implementing prevention, the principle of combining prevention foundation. Subjects and methods 1. Target: 1992-2004 7 counties in this area, there are habitual abortion, infertility, birth stillbirth, birth defects, mental retardation, congenital disease, successive generations of the family and other genetic diseases were 2308 cases. Age coverage of newborns born 1 h to 57-year-old adult .0 years old accounted for 14.73% (340 / 2 308), 3 years old accounted for 8.70% (201 / 2 308), 6 years old accounted for 7.86 % (182 / 2 308), 13 years old accounted for 29.85% (689 / 2 308), 18 to 57 years old accounted for 38.82% (896 / 2 308); rural areas accounted for 56.14% (1302 / 2 308), the city accounted for 49.58 % (1 006 / 2 308), men accounted for 52.12% (1203 / 2 308), women account for 43.97% (1015 / 2308). 2. Check the contents: All patients with peripheral blood lymphocyte culture or amniotic fluid cell culture, chromosome karyotype, G, C, R, Q banding techniques, metabolic genetic disease related to patients with incurable diseases can be checked. Results Chromosome abnormalities detected in 109 cases of nuclear type, the total number of 4.72% (109 / 2 308); often abnormal number of chromosome abnormalities accounted for 81.65% (89/109), the number of sex chromosome