Combined with low doses of quetiapine in the treatment of insomnia clinical observation.docVIP

 PAGE \* MERGEFORMAT 8 Combined with low doses of quetiapine in the treatment of insomnia clinical observation [Abstract] Objective and low dose quetiapine for insomnia treatment. Methods 26 cases of insomnia combined with low doses of quetiapine in the treatment efficacy. Results combined with low doses of quetiapine in the treatment of insomnia 15 days, SDRS scores were significantly higher than before treatment decreased, the difference was statistically significant (P lt;0.01, the effective rate was 73.1%, 69.2% of the patients of the original hypnotic dose reduction, TESS scores, the difference was not statistically significant (Pgt; 0.05, no new adverse reactions. Conclusions Short-term and low dose quetiapine in the treatment of insomnia can increase, without increasing adverse events. [Keywords:] quetiapine in the treatment of insomnia Insomnia is a very long time sustained the quality of sleep and / or the amount of unsatisfactory conditions. At present, drugs for insomnia, more benzodiazepines still the main drugs, but the benzodiazepine class significant risk of side effects and the formation of dependence, it is non-benzodiazepine class of drugs used widely, but the repeated use of the situation is still well tolerated, the dose will continue to increase, increase in adverse side effects, for the expansion of new ideas and methods of treatment , now using low dose of quetiapine treatment of insomnia method, 26 cases are summarized below. 1 Materials and Methods 1.1 General Information cases from Guangxi Longquan Hill Hospital psychiatric clinic, in line Chinese classification and diagnostic criteria of mental disorders (CCMD-3) insomnia diagnostic criteria [1], exclusion combined with other mental illness, rule out alcohol or other drug dependent persons, rule out serious organic diseases, pregnancy or breast-feeding women, patients taking drugs when the type of treatment include alprazolam, estazolam, clonazepam, zopicl