Compound mifepristone and misoprostol for luteal phase contraception clinical study.docVIP

 PAGE \* MERGEFORMAT 10 Compound mifepristone and misoprostol for luteal phase contraception clinical study [Abstract] Objective To explore female luteal phase mifepristone with misoprostol for application of compound efficacy and safety of contraception. Methods of contraception-free sex life many times (no contraception intercourse without contraception or sex requirements attracts over 120 h 285 cases of women emergency contraception, menstrual cramps in the first 10 days is expected to take mifepristone compound and was taken after 48 h of compound mifepristone plus misoprostol. to observe whether the situation of pregnancy and the next menstruation. Results 5 cases of 285 pregnant women, the failure rate 1.8% .280 patients had menstrual cramps, bleeding luteal start early group was significantly earlier than the other two groups (P lt;0.05, the duration of bleeding among the 3 groups had no significant difference in the normal menstrual basically the same period, major adverse drug reactions during diarrhea, abdominal pain (35.3% and nausea and vomiting (26.5%, adverse reactions, can relieve itself. Conclusion The use of luteal phase mifepristone with misoprostol compound , is a safe, effective contraceptive remedies. [Keywords:] compound mifepristone, misoprostol, luteal phase, emergency contraception [Abstract] Objective To assess the efficacy, safety on compound mifepristone with misoprostol for emergent contraception in luteal phase.Methods 280 women who were exposed to no contraception intercourse more than five days or having had more than one episode of no contraception intercourse in the same cycle were investigated.285 women were divided into three groups according to luteal phase of the cycle (93 cases in earlier period, 93 cases in middle period and 94 cases in later period.The two medicine were took by all subjects.Results After treatment 5 women (1.7% were pregnant and 280 women had return of menstruation.Women in earlier period group