Danshen on renal cortex of rats with obstructive jaundice of blood perfusion.docVIP

 PAGE \* MERGEFORMAT 12 Danshen on renal cortex of rats with obstructive jaundice of blood perfusion Of: Qinqi Yu, Li Yong, Jin-Jun Chen, Qing-Fu Zhang, Wang car Jiang, WANG Wei [Abstract] Objective To investigate the renal cortex of rats with obstructive changes in blood perfusion and therapeutic effects of Danshen. Methods SD rats were divided into sham operation group (A group, bile duct ligation group (B group, Danshen intervention group (C groups, each sub-3,7,10 d 3 time phases, each phase 8. Application LISCA laser Doppler tissue perfusion and blood perfusion imager observations of each group of image analysis system corresponding phase of renal cortical blood perfusion changes. test blood urea nitrogen (BUN, creatinine (Cr level. Results A group B group and each time the value of reduced renal cortical blood perfusion and more pronounced decrease with time (P lt;0.05.7,10 d The blood BUN, Cr levels (P lt;0.05.C group and B group at each time the value of renal cortical blood perfusion increased (P lt;0.05,10 d The blood BUN, Cr levels decreased (P lt;0.05. Conclusion Obstructive jaundice can lead to renal cortical blood perfusion decreased, Danshen injection can increase the renal cortical blood perfusion. [Keywords:] Jaundice, obstructive, kidney, blood perfusion, Danshen injection Abstract: ObjectiveTo research the alteration of the renal cortex hemoperfusion in obstructive jaundice rats by salvia miltiorrhiza. Methods72 SD rats were divided into 3 groups, which were false-operation group (A), commen bile duct ligation group (B), and salvia miltiorrhiza group (C). The rats were observed on the 3rd, 7th, 10th day, and each observe time had 8 SD rats.The renal cortex hemoperfusion and the renal function (BUN, Cr) were observed by LISCA laser Doppler Hemoperfusion image instrument in different phases.ResultsThe renal cortex hemoperfusion in group B was less than group A, and was the least in the 10d phase (P lt;0.05). In the 7d and 10d phase,