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Deep nosocomial fungal infection risk factors
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Deep nosocomial fungal infection risk factors
[Abstract] Objective: To investigate the occurrence of deep fungal infection in hospitalized patients the risk factors provide a basis for clinical prevention and treatment. Methods: Between 2003 and 2007 in our hospital-patient treatment for all patients discharged from hospital discharge diagnosis of deep fungal infection in line with the 176 patients were retrospective case analysis, the factors that may affect the prognosis of single factor analysis and Logistic regression analysis. Results: The single factor analysis selected 7 and infection-related risk factors, and then by Logistic regression analysis showed that patients with sepsis-related risk factors: age ≥ 60 years, the use of antibiotics and the time of ≥ 3 Zhong ≥ 2 weeks, the use of sugar of corticosteroids and immunosuppressive agents ≥ 2 weeks, and suffering from cancer. Conclusion: The use of hormones and immune inhibitors in elderly patients, as well as cancer patients are deep fungal infection in high risk of death. Effective control of risk factors may be related to prevention and treatment of deep fungal infection in the key.
[Keywords:] deep fungal infection; risk factors; Logistic regression
In recent years, with broad-spectrum antibiotics, immunosuppressive agents and a variety of invasive procedures and the extensive use of parenteral nutrition, as well as the AIDS epidemic, nosocomial fungal infections in patients with markedly increased [1]. Deep fungal infection on inpatients is a deadly threat. In this study four years of deep fungal infections in-depth investigations to explore the risk factors leading to fungal infections, using a single factor and multi-factor analysis method to determine the deep fungal infection of the major risk factors for deep fungal infection and provide a theoretical basis for early diagnosis and treatment of .
1 Data and methods
1.1 Case Selection
Choose to January 2003 ~ Au
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