Dendrobium treatment of atrophic gastritis in rats with experimental medical research.docVIP

 PAGE \* MERGEFORMAT 12 Dendrobium treatment of atrophic gastritis in rats with experimental medical research Study: Pan Xiao-yan, Li talent, Zhouxi Han, Yin Yixia, Pan Xingshou [Abstract] Objective Dendrobium treatment of chronic atrophic gastritis (CAG) of the effect and its mechanism. Methods ammonia, ethanol and sodium deoxycholate gavage method, made #8203;#8203;of CAG rat model. The treatment group after the model of Dendrobium treatment for 5 weeks, and blood gastrin (GAS, somatostatin (SS and gastric mucosal prostaglandin E2 (PGE2 changes, and with the model group and control group. Results Dendrobium before treatment, SS, GAS, and PGE2 were is 7.95 + -2.14 ng / L, 216.13 + -77.21 ng / L, 1435.10 + -200.53 pg / mp, compared with the control group (P lt;0.01, respectively, after treatment 9.58 + -1.01 ng / L, 328.53 + - 84.74 ng / L, 1715.66 + -125.49 pg / mp, after treatment, except SS, each index were higher than those observed before treatment with high (P lt;0.01, compared with the control group, no significant difference (Pgt; 0.05). conclusions can Dendrobium GAS and PGE2 increased, the CAG has a good therapeutic effect. [Keywords:] atrophic gastritis; Dendrobium; rat [Abstract] Objective To study the effect and mechanism of dendrobium for treatment of chronic atrophic gastritis (CAG). Methods The rat of CAG model was made by pouring ammonia water, alchol and sodium deoxycholate into stomach. The treatment group were given dendrobium for five weeks. The blood gastrin (GAS), somato statin (SS) and prostaglandin E2 (PGE2) were observed.They were compared with control group.Results the SS, GAS and PGE2 in treatment group were 7.95 + -2.14 (ng / l) , 216.3 + -77.21 (ng / l) and1435.10 + -200.53 (ng / l) respectively before treatment, which were lower than those in control group (P lt;0.01). the SS, GAS and PGE2 in therapy group were 9.58 + -1.01 (ng / l), 328.53 + -84.74 (ng / l) and1715.66 + -125.49 (ng / l) respectively after the treatmen